举个例子,unlike traditional small molecules, biological products can be barely manufactured in an exactly form from one lot to another, let alone by different manufacturer. 这个在国会还在争论法律上需要什么去证明generic and original are the same in their biological and pharmacological properties. Therefore, the current trend is that big pharms are speeding up buying out small, medium or even well established biotech companies, especially in US in order to gain growth momentum, even though there are common challenges in drug pricing pressure and competition.